Hi Ichigo,
That's perfectly normal to not necessarily hear a difference between a crossover frequency of 40 Hz and 80 Hz for the M22. And although JohnK and I politely disagree on the virtues and limitations of Audyssey, may I suggest that you not become overly reliant on its calculations. Audyssey and similar systems may be hit or miss and tend to be error-prone.
The default crossover setting for the M22s that tends to work very well in most applications is 80 Hz. Using that allows the subwoofer to gradually take over the deep bass duties so the little woofer/mids in the M22 don't have to "work" as hard and so play more cleanly. Set the M22s to "Small".
Alan
Over the years, I have tried several speakers of different sizes and configurations along with a number of crossover points, however, one common thread emerged from all my experimentation, in that, I found there was a "method to the madness" of the folks at THX when watching movies, that they chose to establish a standard of 80HZ as a crossover point. For most, it just seems to be the "right" setting and with that in mind, myself having both M22s AND M80s, I fully concur with Alan's comments.