Stilljoe, what is the size of your room? I'm currently deciding on a setup with M22s and either a VP150 or VP160.
My room is just 16 X 11 X 7.5. TV mounted on a short wall with the VP150 below on a cabinet, tilted up (by turning it over and flipping the grille). Fronts are (very) old Boston Acoustics floorstanders until later this year, when I can hopefully pick up M60s. I sit 8-9 feet back from the TV and centre speaker.
Majority opinion would say the 160 is more desirable. We found both good but - personal preference - we liked the 150 better.