Drew, welcome. Yes, an M3 would work as a vertical center with M22s, but unless you have some specific reason for preferring the M3, the M2 might be a better choice. The M2 is an almost exact match in timbre for the M22s above about 90Hz, while the M3 uses a different driver with a slightly different(although very good)sound.

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Enjoy the music, not the equipment.