Sub placement in a room is very important, every room is different. Most likely that position will work, but won't be the ideal position for the room. Most people experiment with various locations to get the best sound, may be the corner, may be the side wall, etc...

The frequencies from a sub are low and emit in all directions, not sure it would be a good idea to put it in an enclosure.

M80s VP180 4xM22ow 4xM3ic EP600 2xEP350
AnthemAVM60 Outlaw7700 EmoA500 Epson5040UB SonyUBPX800