Troy I would say as far as your back speakers if you listen to more music then movies direct might be a good way to go. If you are about half the Q's are hard to beat they are good for music too. I tried my M22's in the back of the room as surrounds in a 5.1 set up about 8 1/2 feet away they were not as diffused as the Q's but worked great. I felt like it served both rows in my room better the M22's image well. So it is just personal taste so yes if you had the room I would say F/R 80's VP 150 center, and M22's rear.
Thanks Steve