Get the M22s at least if not the M60/M80s as your room is quite large and you are sitting a fair ways back of the mains. The performance upgrade to Axioms from the little Take 5's is quite noticeable, IMO, not that the Take 5's are bad by any means, I quite like them.

Just curious as to what subwoofer you are using as the M22s need a sub to really show off LFE for movies as do the Take 5's?