I think I may be the only active board member who still has M50s.
I've got your back, man!
I really like my M50's. However I haven't compared them to any others. I bought mine for two reasons . . . I - A very tight budget . . . II - With 4 kids (oldest is 6) I didn't want any stand mounted speakers like the M22 so I went with the towers.
I've been very happy with them. I'm also running the VP100 for a center channel. Like others have mentioned, if I had the VP150 I'd also lean towards the M60's.