The best match for the M22 is the M22. If you don't have enough room then an M2 would be next. If vertical space is still an issue I'd still take the VP150 over the VP100, just because the extra driver and cabinet size does increase bass output over the VP100.
Would this be horizontally mounted? I really don't have room on the wall to vertically mount an M22 above or below the screen. If horizontal, does the tweeter being offset to one side matter? I would think that it would.
Bass output is less of an issue as I'll be building a cabinet for a 15" sub which should have plenty of output for a room of this size.