Right now I am thinking of:
Pair of M60's
VP160 with stand
QS8's with stands.(Wall mounting is not an option in my room the way it's configured.)
Or a step down:
Pair of M22's with stands
VP160 with stand or VP 150 or M2 as suggested.
QS8's with stands.
Given that you have the space and $, go for the M60 package. I have both the M22s & M60s. If you step down, you'll be more susceptible to "upgradeitis". That means you'll end up with both sets...which, on second thought, just might be the perfect solution!