Having listened to various combinations of speakers at Axiom before here is what I think:

M22 + Sub = M60 with a much better bottom end

The M80 is considerably better than the M60 in the bottom end and subtly better in the mids and treble.

They are all very good speakers. I'm curious why you do not have the M100 on your list. If you are listening 2 channel, then these would appear to give you the best bass of the lot.

Fred

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Blujays1: Spending Fred's money one bottle at a time, no two... Oh crap!