So I'm planning to purchase a Cambridge 651A integrated amplifier soon.

I'm going to stream Spotify and Tidal services through my PC.

I was wondering which setup should i use?

A. M22 with Elemental Design A300 subwoofer.
B. M60 with no sub.
C. M60 with sub.

I already own the M22.v2 and M60.v2 speakers, I just need advice on which one is better to use. Let me know, thanks.

I dont know much about that sub.

Generally, going towers and sub will let you crossover the bass lower. Bookshelves may need to be a higher setting.

A similar outcome can be reached using either of your sub + speaker setups. If your room is large towers and sub. If small bookshelves and sub. In my experience, it is easy to let bass frequencies get away from you. Balance is key.

Since both of those speakers are similarly voiced, I would agree with this. I do recall the M22s being a bit more forward, but it is a subtle difference.

if you already own the speakers, have you not listened to them yet? or is this a case where you own the speakers and have not listened to them yet and that's what the IA is for? I'm just trying to make sure I understand everything.

best of luck and keep us posted buddy!

I have M22 and M80, Upgraded due to really wanted towers.
If you like more boom go the M60. I find the soundstage with my towers and subs to be huge. I love it {full emersion}.

Ultimately use the sub either way, as all music and movies are going to have bass, and the sub is going to help your system.