My configuration is M22 fronts, VP150 center, QS8 side surrounds, and M2 rears with an SVS PC13 sub all driven by a pioneer VSX-45. I listen to stereo source material in 7 channel stereo mode and it sounds fine to me.

If I had to do without a sub I would want M80 fronts for their lower end capability, and the VP180 if I could rationalize the expense. I wouldn't change the sides or rears because I don't think there would be significant difference. Just my opinion of course.