I haven't heard the M3s, but I have heard the M22s, M60s, and M80s, and I own the M50s. The M80s were my favorite of the bunch, but a leetle out of my price range and room size... I really really like the M22s-they have an excellent soundstage, and make you go "Wow!" which is my main qualifier in a speaker. Actually, all of the Axiom line does that for me. The M50s are a bit more laid back than the 22s and 60s; when I compared the 22s and 50s back to back, the 22s were better on some stuff, and the 50s were better on other stuff. The 60s were enjoyable, but I spent most of my time with them trying to get DenonLINK to work with SACDs, so I wasn't exactly listening critically.
Basically, you can't go wrong. Get both the 3s and the 22s.
