If you have a sub, I would say small with an 80hz crossover on the receiver, and turn off/bypass the crossover knob on the sub. I have a 51" x 120" screen, and the vp150 is mounted below the screen. Keep in mind when you in the seated position, you want your eyes to be 1/6th to 1/3rd up from the bottom of the screen. You normally want your left/right tweeters as close as possible lined up with the center.

M80s VP180 4xM22ow 4xM3ic EP600 2xEP350
AnthemAVM60 Outlaw7700 EmoA500 Epson5040UB FluanceRT85