Both are terrific. I'd suggest trying to demo both and deciding for yourself. Both have a very similar sound. Being a bit larger, the Ascends go a bit deeper and sound a bit fuller. Though the M22's are a touch more detailed in the midrange and high end. You really need to hear them.
I'd suggest trying to find an owner who'll open their home for an audition, or better yet, buy a pair of both...keep one pair, and send one back. Return shipping on either wouldn't be too much, and then you'd know for certain you bought the best pair for you.
Good luck. You've certainly narrowed your search down to a couple of great choices.
