Others here can correct me if I'm wrong, but, I don't think you're going to find a better midrange by upgrading to the M60ti. I think the difference between the M22 and the M60 lies in the extended bass of the floorstander and its ability to play louder. Since the M80s have two of everything, that might be the beasts your wife is looking for. By the way, I have the M22s and my wife likes them fine. I wish she hated them, though.