It would be a good idea to uninstall any drivers you can find in Add/Remove Programs and reinstall them after the upgrade, specifically video drivers. On the other hand, you will want to install any mass storage device (SATA or ATA) drivers for the NEW motherboard BEFORE the upgrade. This will prevent a nasty BSOD if Windows can't find the correct driver. This is your biggest obstacle. Windows SHOULD detect the primary SATA or ATA controller natively but there are no guarantees. If the bootstrap program decides your HDD or HDD controller is not available or has changed in a way it can't understand you will get the BSOD. So make sure the SATA driver especially is installed before the upgrade. Video drivers are the second critical part. Windows can get very funky with corrupt or incorrect video drivers. Also, if you are using embedded audio go ahead and uninstall the drivers and install new ones for the new chip.
