The M22's are "better" than the M3ti's. They have a different sound. The M3ti is a more "laid back" sound, where the M22 is more crisp and clear. Some people like one sound over the other. It really depends on which sound you like. Most Axiom owner prefer the clarity of the M22, but it's really up to you and your ear.

The VP150 on the other hand is a different story. I've never heard the VP100, but it's pretty unanimous around here that if it's feasible in your budget, get the VP150, so that's what I did, and have not regretted it. The VP150 is great.

Just a quick note on Axiom speaker characteristics...

Laid back/Subdued

M3ti
M40ti
M50ti

Crisp/Clear

M2ti
M22ti
M60ti
M80ti

Sounds like you're going to have a great new system. Enjoy!