So I take it you are now looking at the bookshelves? The M22 is the more detailed of the bookshelves, more along the same line as the M80.

Surrounds like the QS8 can be put virtually anywhere you can squeeze them in and still have great surround envelopment. But I would go with equidistant and backs to open room, as I prefer to have my affects coming from the rear/side opposed to front/side and I beleive THX specs recommend closer to rear or rear than in front of you.

Jason
M80 v2
VP160 v3
QS8 v2
PB13 Ultra
Denon 3808
Samsung 85" Q70