The M22 is very detailed, the M50s are more laid back. The vocals and mids come through with the same or more intensity as the bass on the M22s. It is the other way around for the M50s.

Just because a speakers response is the same as another they can have very different sonic characteristics.

Jason
M80 v2
VP160 v3
QS8 v2
PB13 Ultra
Denon 3808
Samsung 85" Q70