When I did an a/b comparison at Axiom, I heard very little difference between the M22+ sub and the M60. Yes, the sub delivered more bass, but the mids and highs were almost identical. In fact, I noticed more difference between the M80 and M22 on the mids/highs.
The M22 was quite forward compared to the M80. Strangely, the M60 does not sound forward compared to the M80 or recessed compared to the M22. Never quite understood that.
I found the M80 had more detail in the highs than either the M22 or M60. What you get with an M82, I don't know.