Your TV will use the HDMI output on back of receiver and everything else will use HDMI inputs, buy a receiver that has more HDMI inputs than you think you will use. I don't know much about game systems but I don't think you can use HDMI for a Wii it use component video, which you can plug into the component input and the receiver will send it over the HDMI output to TV. Majority of receivers only have 1 subwoofer rca input (LFE) but yeah you can always daisy chain more than one sub together.