I have the M22's up front,and I love them.If your 50% 2 channel music,you would want nothing else but M22's, they sound great.I have VP150 center up front,which I would suggest to get as well.I tried both VP100 & VP150 at the retail store before I bought,their is a big differents.For size of room I would Get the VP150.
I also have the QS4's as rear surrounds ,on the back wall behind the lisener.Which sound great aswell.