I have the 53TX predecessor, 45TX and love it. The MCACC is a good feature for me, though that brings up a can worms... It works for me and I'm happy.

I think the only complaint when moving from the 45TX to the 53TX was that the remote was scaled down in features. No biggie, I use a Harmony 688 anyways. Featurewise, the Elites hold their own. My understanding is that the Yammy 2400 and others have a similar MCACC. Although I somehow recall on one of the threads here that there was some "issue" with that. I could be remembering wrong.

I use my 45TX to drive M22s, VP150, QS8s, Tivo, Denon 2200 DVD, VCR, Plasma, HD DirecTV recv (HD Tivo on order), and Gamecube. The main reason I got this receiver was because of Sushi's recommendations.