Following on my great success at guessing the highest volume Axiom speaker, my guess is that you will be OK with on EP350 as long as you get the placement right.

At first glance the M60s in the corner seem too far apart for the seating position; once you move them in a bit you should have room for the EP350 in the left corner

M60ti, VP180, QS8, M2ti, EP500, PC-Plus 20-39
M5HP, M40ti, Sierra-1
LFR1100 active, ADA1500-4 and -8