Jake, you should go with the M22s plus a sub, even if your budget requires spending a little less on the sub. There are some quite good subs in the $200-$250 area that would work nicely with M22s. I'd suggest you take a look at the Bic America V1215, which you could get for about $250 delivered from sources such as etronics.com. Not fancy-looking, but subs are meant to be heard, not seen.

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Enjoy the music, not the equipment.