Mark, your proposed setup up should be excellent in a room of that size. If you've run into some of my replies you know that I prefer a vertical M2 as center rather than even as well-regarded a horizontal center as the VP150. M22s plus 25-31PC(ask Tom to tune it to 22hz)would be about as good as it gets for stereo music listening. Note of course that you can use DPLII on stereo recordings to see how you like the ambience effects.

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Enjoy the music, not the equipment.