Thanks Dan, yep I found that article the other day. I'm still tossing around my options, possibly just setting up a mirroring scenario. Again, I just plan to use this as a HTPC so I won't be running many applications other than TheaterTek DVD software and the OS itself, which would reside on my primary drive. I was planning on using the extra hard drives for ripping my CD's and possibly some of my DVD collection so I don't have to get up often to swap out the DVD's in the player. I also plan to add an HDTV tuner OTA card at some point. Not sure about adding a PVR card yet.
Maybe my best bet would be to use like a Raid 1/mirrored environment?
M80s-VP180-QS8s-EP600-2xEP350 Denon3808 Outlaw7700