If you're implying that the greater bass extension compared to the M2s wouldn't really be an advantage if you have a sub to handle the low bass, you're right. However, a couple of the other replies have questioned whether the M2s would play loudly enough with low distortion in your size room. I don't know if that would really be a problem, but the M22s have more capacity to play loudly with low distortion.

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Enjoy the music, not the equipment.