For music, I find the M60s just about right, ie I prefer listening to M60s on their own without a sub and I wouldn't want the bass pumped up any more. For movies, it's no contest... the M60s won't go deep enough (nor will any other conventional tower speaker) to replace a good subwoofer.

M60ti, VP180, QS8, M2ti, EP500, PC-Plus 20-39
M5HP, M40ti, Sierra-1
LFR1100 active, ADA1500-4 and -8