The M22 + sub sounds very good but the floorstanders sound that much warmer/fuller. I have listened to M22+EP600 and the M60 and M80s, all with in minutes of each other...no contest M60s or M80s wins out; to downgrade would not be unliveable, but noticably a downgrade in sound,IMO. If you never compare the 2, you most likely won't know what you were missing though.

Jason
M80 v2
VP160 v3
QS8 v2
PB13 Ultra
Denon 3808
Samsung 85" Q70