MB, as far as the hardwood floor goes, it's generally good to have a rug or two to tone down the liveliness. As far as the sub with M22, however, this shouldn't change the basic principles; set the sub in the tighter(i.e. farthest from a doorway or other large opening)corner behind an M22 and set the receiver crossover(if available)to 80Hz.

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Enjoy the music, not the equipment.