I haven't had the chance to listen to the M22 but I did recently set up my sister with a pair of M3's (I'm moving and am taking my M60s with me).
I'm really quite impressed with the M3's. They sound great for the vast majority of music that we listen to and manage to fill our 16X12 room with lots of sound.
The only caveat that I would offer is that for electronic music, or any other bass heavy music, they may leave you wanting just a bit more low end. Then again, this should be fairly obvious given that they are bookshelf speakers and may very well be me being used to the M60 sound.
For a small office, I would say that the M3s would be my first choice. However, I'm sure that the M2s or M22s could do the job as well.
Best of luck.
J
