If two channel only - M80ti
If Home Theater - M22ti + HIGH quality sub
If both - M22ti + HIGH quality sub

Based on the information given, the M22 should have enough bass output to crossover at even 60Hz, although 80 Hz is no problem. The trick is that you have to really invest in a very high quality subwoofer.

If you look at the M60 and M22, the only real differences are the woofers and likely the corssover points (due to the differences in drivers). However, the drivers are identical in construction.

The M22 has an additional mid-woofer, presumably to give better mid-bass output (versus the M2 for example). A high quality subwoofer WILL fill that gap for the lower frequencies.

The other nice thing about the M22 is that you can use the full metal bracket to hang it from the wall to avoid any knock-over issues and the bracket is, for all intents and purposes, "invisible" while listening. If you can install wall plates then you cabling becomes "invisible" as well.

In purchasing the M60 and a high quality subwoofer you start to enter that "overkill" area which some people tend to prefer. I don't believe that you need it, but if you want it, then that is an option. For the extreme overkill there is always the M80s with a subwoofer.

Bottom line is that a pair of M22s with quality sub will be more than adequate.