Why not consider one of the other floorstanding models? My room is bigger than your and the 60's work great. With a sub, I'm sure the W22's would be fine and perform similar to the M22's. Neither one will give you the same bass performance of the 50's, 60's, or 80's for a better blend of low sounds.

M80s VP180 4xM22ow 4xM3ic EP600 2xEP350
AnthemAVM60 Outlaw7700 EmoA500 Epson5040UB FluanceRT85