I tried searching on this but I'm probably not searching for the right terms. Let's say you wanted to run two sets of mains (M80s for example) and you have mono blocks for each speaker. Is it a simple matter of running the preouts into y cables and then to the amps? The left preout would feed a pair of amps via a y cable and subsequently a pair of M80s and the right preout would do the same.

Another option would be to only use a pair of amps with the speakers run in series. This would create a 2 Ohm load on each amp (I believe) and would assume the amps could handle the 2 Ohm load.

Is one better than the other? Another option?