a) I think the m22's would be fine, as would the 2's, 3's, 50's, 60's, or 80's.

b) Others will chime in as they have 22's in larger/smaller rooms.

c) I prefer Axiom subs, just because they have matching finishes and it is hard to beat a 500 or 600, if you can afford one.

M80s VP180 4xM22ow 4xM3ic EP600 2xEP350
AnthemAVM60 Outlaw7700 EmoA500 Epson5040UB FluanceRT85