Jimmy,
I assume that you are trying to get the most speaker for your money. I have M22s in a slightly larger room than yours and they do a fine job. One thing to remember when considering your options between bookshelves/floorstanders is that most tower speakers can be run in 2 channel mode without the use of a sub. If your ok with running the sub full time, bookshelf speakers are fine. If not, you should look at the beta 50s a little closer. Another thing you have probably considered is that the low price on the infinity setup is probably from an unauthorized dealer, whereas the Axioms are coming directly from the manufacturer with a record of having a stellar customer service history.
