Although I haven't purchased any Axioms yet, I have run through the Home Theater Wizard a couple of times.

On paper my dedicated theater room is 14-8 W x 21-4 L with a ceiling height of 9-2. That's only 313 square feet, but almost 2900 cubic feet of volume. By the HTW, that is barely considered a "large" room, but the recommendation for a 7.1 system is for M60s, a VP150, 4-QS8s, and the EP500. Your type of movie/music listening will change what is recommended, too. And from what I'm reading here, you're probably wasting money by going with the M80 unless you've got a really long room (>25') and an amp that likes 4-ohm loads.

I will be running a pre/pro combo of some sort (in the 200WPC range), so power won't be a problem. But I haven't figured out which one yet. That's a question I need to ask in another thread.

Best of luck in your decision.