Joe, welcome. The M22s are excellent in a room that size. Although the EP500 could be considered a bit of overkill, it can be calibrated to a level to suit the room; speakers can never necessarily "overpower" a room if they're calibrated correctly.

The 3808 is fine; if you wanted to save a bit there, you could consider the 2808(988)unless some feature unique to the 3808 is really wanted.

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Enjoy the music, not the equipment.