Rick, I agree, his Denon would not have an issue with the 80's. Heck, I have the Denon 2805 which is pretty much the same. Having owned the 60's as well, I would also consider them as well. The 22's are great speakers, but I like the extra presence the 60's and 80's will add.
The vp100 or 150 is a toss up. I've only owned the 150, but have heard the 100 is very similar. I would say you could go either way in that room size.
The Q surrounds are the best in the industry, in my opinion. If budget allows I would say get the Qs8's. The extra sized woofers and extra power ability are worth the extra cash.
If you decide to go with an Axiom sub, I would get at least the VP350v3 which is a great sub for the money. Or, step up to an EP500.