They are supposed to sound very similar, with the slight edge going to the M22's. I wanted the best bookshelves available and the M2's would look mighty silly on the sides of my VP150. But I am sure that with a sub, the M2 is a much better speaker than the M3. I am also guessing the M22's have a little more bass than the M2's considering the box is twice the size. That is why most people go with the M22's.