NC, maybe I don't have the right impression of your room, but assuming that the TV was in the alcove, the mains don't also have to be there. If the room is about 20' wide and you're going to sit at least 10' away it would seem that the mains could be separated a foot or more wider than the alcove. As long as there's at least 3" of breathing room for the rear ports, that placement should work well. In that size room M60s would be fine if you prefer towers.

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Enjoy the music, not the equipment.