I don't now why I'm posting this because my 22tis and VP150 haven't even arrived yet. However, that question has been asked and addressed on this forum before. And, from everything I've read here, you'd be OK with either center speaker. It just depends on the size of your room, the location of your seating, and the way it's positioned in the room. If I understand what I've read, it's not that the 150 SOUNDS better than the 100, it's that the 150 has wider dispersion because of the arrangement of the drivers. You should be just fine with the 22tis and the 150. I'll let you know what I think when mine arrive.
Maybe others here can be more specific.
