Hello, yello; welcome. Since even when a sub is used for the low bass, the M22 has two of the 5 1/4" drivers handling upper bass/mid-range, rather than one as in the M2, it can play those frequencies at a louder level with low speaker distortion. Whether that's meaningful in a particular application would depend mostly on listening distance and average sound level used. The treble frequencies should be essentially identical.

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Enjoy the music, not the equipment.