I have both the M3s and the M22s, and while I really like the M3s, I love the M22s. That said, I run them both with a sub. If I wasn't using the sub I may have to go with the M3. And that's pretty much what Axiom will suggest too; as the M3 has a slight mid-bass bump in it's frequency curve.

To be honest, if I couldn't run a sub I'd probably find a way to run M60s.