Hi Nickbuol,
So long as the framing supporting the acoustically transparent "wall" isn't too elaborate, you should be OK, at least for home theater playback and casual listening. The diffraction effects from the framing might mess up the stereo soundstage and imaging a bit for ultra-critical listening, but frankly, it's not a comparison I've ever made. All the double blind tests I've done have used an acoustically transparent curtain hung from a track on the ceiling, so there isn't any framing to potentially mess up the soundstage.
You could always run an experiment with the frame and "wall" temporarily in place, if that's possible, and compare it to the sound quality with no obstruction.
Regards,
Alan
