You're in GA; I think some Axiom owners in Atlanta give auditions. Check out the "Auditioning Axioms in Your Area" thread in the Questions and Answers forum.

I've had M22 bookshelves plus a Hsu STF-2 sub, then M60s with the STF-2, then M60s and no sub, then with a VTF-3R. My room is 16 x 20 and I like plenty of bass.

M22s plus the STF-2 were amazingly good. But there's no question M60s and a sub are better, even a modest one like an STF-2. That said I can understand how some people like M60s with no sub. It's got plenty of bass and sounds great; I just like that extra kick in the chest.

Re M22s with sub vs M60 and no sub for music alone, that's a tough call. For an immediate choice I'd marginally take the M22s plus a sub. However in the long run I'd be happier with M60s and getting a sub later whenever I could afford it. That would best fit my music tastes; many are perpetually happy with M60s alone for music.