Troy, then since you'll be using a good sub and crossing the center over at 80Hz, a good choice is the M2. It has the identical tweeter over mid-range as the VP160 and above about 80Hz is nearly identical to the M22(the dual drivers in the M22 would allow for louder output in the upper bass and mid-range). If the height of the M22 makes it unacceptable for use as a center in your setup, note that the 11 1/2" height of the M2 is identical to the VP160 height and would fit in the same vertical space.
I am just concerned a bit about performance levels. My room is
a bit over 2100sq ft.
I am taking the M22 into work we have a board room pretty well the size of what my movie room is going to be. IBrent emailed my today with my question and it maybe I might have to go with the M60's