I'm assuming you meant the VP100 center channel? If so, then the M2i mains, VP100 center and QS4 surrounds paired with that Hsu STF-2 sub will blow your mind in a room that size.

BTW...why that panasonic receiver? Is it because it's really small, or because it's $300?

If it's the price, I'd recommend trying this Onkyo.